書誌事項
- タイトル別名
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- Effect of co-supplementation of high dose of vitamin B_1 and fat on glucose and lipid metabolism in the porcine liver
- コウノウド ビタミン B ₁ ト シボウ ノ ドウジ セッシュ ガ ブタ カンゾウ チュウ ノ トウシツ ・ シシツ タイシャ ニ オヨボス エイキョウ
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We examined the effects of vitamin B_1 (B_1) and fat added to a feed on their accumulation and glucose- and lipid-metabolism in the porcine liver. B_1 content in the livers of pigs fed a feed supplemented with 15 ppm B_1-supplemented feed (B+ group) was significantly higher than that in the livers of pigs fed the usual dosage of 1.5 ppm B_1 (Control group). B_1 content in the livers of pigs given a feed with 1.5 ppm B_1 plus 3% fat (F+ group) or a feed with 15 ppm B_1 plus 3% fat (B+F+ group) was significantly higher than that in pigs given a feed with 15 ppm B_1 (B+ group) or controls. The liver fat content in the B+F+ group was lower than that in the B+ group. Analysis of liver mRNA levels showed that gene expression of β-oxidation-related proteins increased in B_1-supplemented groups. Glycolytic pathway- and TCA cycle-related gene expression levels were also increased with fat supplementation. These results indicated that, in pigs with co-supplementation of high dose of B_1 and fat, glucose and lipid metabolism was enhanced in the liver.
収録刊行物
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- ビタミン
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ビタミン 87 (10), 543-548, 2013
公益社団法人 日本ビタミン学会
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詳細情報 詳細情報について
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- CRID
- 1390282680645871360
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- NII論文ID
- 110009674990
- 40019841046
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- NII書誌ID
- AN00207833
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- ISSN
- 2424080X
- 0006386X
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- NDL書誌ID
- 024954813
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可