Relationship between the inhibitory effect of ginger (<i>Zingiber officinale</i> Roscoe) on nitric oxide production and the drying conditions after harvest

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  • Fuchino Hiroyuki
    Tsukuba Division, Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation (NIBIO)
  • Tanouchi Kana
    Faculty of Pharmaceutical Sciences, Tokyo University of Science
  • Daikonya Akihiro
    Tsukuba Division, Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation (NIBIO)
  • Wada Hiroshi
    Faculty of Pharmaceutical Sciences, Tokyo University of Science
  • Iida Osamu
    Tanegashima Division, Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation (NIBIO)
  • Sugimura Koji
    Tanegashima Division, Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation (NIBIO)
  • Kawahara Nobuo
    Tsukuba Division, Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation (NIBIO)

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  • ショウキョウ(<i>Zingiber officinale</i> Roscoe)の収穫後の乾燥条件と一酸化窒素産生抑制活性との相関について
  • Relationship between the inhibitory effect of ginger (Zingiber officinale Roscoe) on nitric oxide production and the drying conditions after harvest

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Abstract

In the course of our evaluation of the quality of crude drugs, we examined the conditions under which ginger is processed. In an examination of the relationship between the drying conditions after harvest and inhibitory activity toward nitric oxide (NO) production, we found that drying at a higher temperature gave greater inhibitory activity than drying at a lower temperature. In addition, five constituents were isolated from ginger extract, and their inhibitory activities toward NO production were investigated. Among them, shogaol analogues showed the strongest inhibitory activity.

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