A-27 Extent of osteoconductivity of octacalcium phosphate with coexistence of amorphous calcium phosphate

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  • A-27 リン酸オクタカルシウムの骨伝導能 : 非晶質リン酸カルシウム共存の影響について(生体組織,一般講演(口頭発表),第64回日本歯科理工学会学術講演会)

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Abstract

Octacalcium phosphate (OCP) and amorphous calcium phosphate (ACP) are both precursors in hydroxyapatite (HA) formation. They show osteoconduction by the implantation on mouse calvaria. ACP is known to be more soluble than OCR In the present study, we hypothesized that coexistence of ACP and OCP has an effect on controlling the conversion from OCP to HA, and therefore we analyzed the immersion in simulated body fluid (SBF) and the implantation into critical-sized rat calvaria defect in the mixed granules of ACP and OCP. The results suggest that the addition of ACP to OCP in granule forms may have a positive effect on the osteoconductivity of OCP.

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