S022021 Non- invasive measurement of pressure- diameter relationship of human brachial artery by controlling transmural pressure

Bibliographic Information

Other Title
  • S022021 経壁圧制御によるヒト上腕動脈の経壁圧-血管径関係の非侵襲計測([S022-02]循環器系医療機器(2))

Abstract

A novel apparatus for non-invasive,in vivo evaluation of arterial mechanical properties was developed.A rigid airtight chamber with an ultrasound probe was attached to the upper arm to manipulate transmural pressure(TP) of the brachial artery by changing the pressure in the chamber.Pressure-diameter relationship of the brachial artery was obtained by measuring the diameter with the probe while pressurizing and depressurizing the chamber.Pressure-diameter relationship of the brachial artery could be obtained reproducibly over a wide range of TP.Myogenic response of smooth muscle cells was evaluated by hysteresis area of the pressure-diameter curves.This apparatus may be useful to measure not only pressure-diameter relationship as a mechanical property of artery but also contractility of smooth muscle cell.

Journal

Details 詳細情報について

Report a problem

Back to top