書誌事項
- タイトル別名
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- H-2-4 Cell-based assay device integrated with a microfluidic probe
抄録
In this study, we have developed a microfluidic device integrated with a microfluidic probe to clarify a differentiation mechanism of pluripotent stem cells. It is difficult to evaluate efficacy of chemical reagents for the differentiation using a conventional method because cells cultured in culture dishes are exposed to the reagents homogenously. Here, we propose a novel culture method which enables exposing cells to different chemical condition by location. The device has been evaluated by a computer simulation using FEM, and a flow control experiment. A control of chemical stimulation from single cell level to tissue level in a microspace can be possible by regulating flow ratio and channel size of the microfluidic probe. By using the device, staining of single cell level in a microspace succeeded.
収録刊行物
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- IIP情報・知能・精密機器部門講演会講演論文集
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IIP情報・知能・精密機器部門講演会講演論文集 2014 (0), _H-2-4-1_-_H-2-4-2_, 2014
一般社団法人 日本機械学会
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詳細情報 詳細情報について
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- CRID
- 1390001205899928192
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- NII論文ID
- 110009939201
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- ISSN
- 24243140
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可