2E12 健常者脳主幹動脈における壁面せん断応力一定性の検討

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  • 2E12 Study of the consistency of wall shear stress in healthy major human cerebral arteries

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One of the problems with the cerebrovascular bypass surgery is that the adaptation mechanisms of the cerebral arteries are not clear for the medical professionals to prevent postoperative complications. In order to avoid postoperative complications, elucidation of the adaptation system in human cerebral arteries is necessary. It has been postulated that mean wall shear stress is maintained at a constant value in the arterial system; however, the credibility of the argument needs to be improve to apply the theory at clinical sites. This study investigates the consistency of the wall shear stress of the major cerebral arteries in 7 healthy volunteers using PC-MRI. The blood flowrate and the diameter of the arteries were plotted in the graph with blood flow rate against the third power of the diameter. The linear regression has been performed to see the correlation coefficient (R^2) to study the consistency of the arterial wall shear stress. Results showed a strong correlation coefficient (R^2=0.730±0.204) for the arteries with lower Wormersley number where the Hagen-Poiseuille assumption can be made. Therefore, it can be concluded that the wall shear stress is constant for the major cerebral arteries where the Hagen-Poiseuille flow can be produced.

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