Asymmetric hydrogenation of the C-C double bond of 1- and 1,2-methylated maleimides with cultured suspension cells of Marchantia polymorpha

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Suspension cultured cells of Marchantia polymorpha have a potentiality to hydrogenate the C-C double bonds of 2-methyl- and 2,3-dimethylmaleimide derivatives to give optically pure (2R)-2-methyl- and (2R,3R)-2,3-dimethylsuccinimide derivatives, respectively.

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