Chlorella Viruses

• Yamada, Takashi

• Onimatsu, Hideki

• Van Etten, James L.

抄録

Chlorella viruses or chloroviruses are large, icosahedral, plaque-forming, double-stranded-DNA-containing viruses that replicate in certain strains of the unicellular green alga Chlorella. DNA sequence analysis of the 330-kbp genome of Paramecium bursaria chlorella virus 1 (PBCV-1), the prototype of this virus family (Phycodnaviridae), predict ∼366 protein-encoding genes and 11 tRNA genes. The predicted gene products of ∼500f these genes resemble proteins of known function, including many that are completely unexpected for a virus. In addition, the chlorella viruses have several features and encode many gene products that distinguish them from most viruses. These products include: (1) multiple DNA methyltransferases and DNA site-specific endonucleases, (2) the enzymes required to glycosylate their proteins and synthesize polysaccharides such as hyaluronan and chitin, (3) a virus-encoded K+ channel (called Kcv) located in the internal membrane of the virions, (4) a SET domain containing protein (referred to as vSET) that dimethylates Lys27 in histone 3, and (5) PBCV-1 has three types of introns; a self-splicing intron, a spliceosomal processed intron, and a small tRNA intron. Accumulating evidence indicates that the chlorella viruses have a very long evolutionary history. This review mainly deals with research on the virion structure, genome rearrangements, gene expression, cell wall degradation, polysaccharide synthesis, and evolution of PBCV-1 as well as other related viruses.

収録刊行物

• Advances in Virus Research

  Advances in Virus Research 65 293-336, 2006

  Elsevier Inc.

キーワード

• Chlorella viruses
• PBCV-1
• virion structure
• gene expression
• genome rearrangements
• polysaccharide synthesis and degradation

詳細情報

• CRID: 1050859215941481088
• NII論文ID: 120000882416
• NII書誌ID: AA00514058
• Web Site: http://ir.lib.hiroshima-u.ac.jp/00015041
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles