Etanercept-induced anti-Jo-1-antibody-positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature.

• 湯川, 尚一郎

• 石川, 優樹

• Ohmura, Koichiro

• Hosono, Yuji

• Imura, Yoshitaka

• Kawabata, Daisuke

• Nojima, Takaki

• Fujii, Takao

• Usui, Takashi

• Mimori, Tsuneyo

抄録

Antitumor necrosis factor (TNF) therapy has been associated with adverse immunologic events including systemic lupus erythematosus. However, the development of polymyositis (PM)/dermatomyositis (DM) associated with anti-TNF therapy is extremely rare. We experienced a case of a 48-year-old female with rheumatoid arthritis (RA) who had anti-Jo-1 antibodies and interstitial lung disease but no previous history of PM/DM and who developed PM soon after the initiation of etanercept (ETN) therapy for RA. The patient recovered upon withdrawal from ETN and corticosteroid (CS) therapies. Only four reports of PM/DM associated with anti-TNF therapy for RA could be found in the literature. The patients described in three of the four reports were positive for anti-Jo-1 antibodies before the initiation of anti-TNF therapy, and in all the cases, recovery occurred after the cessation of anti-TNF-agent administration and CS therapy. These results suggest a relationship between the onset of PM/DM with anti-Jo-1 antibody and anti-TNF therapy for RA.

収録刊行物

• Clinical rheumatology

  Clinical rheumatology 29 (5), 563-566, 2010-05

  Springer

キーワード

• Anti-Jo-1 antibody
• Antisynthetase antibodies
• Anti-TNF therapy
• Dermatomyositis
• Polymyositis
• Rheumatoid arthritis

詳細情報

• CRID: 1050001202064952576
• NII論文ID: 120002191883
• NII書誌ID: AA10623843
• ISSN: 14349949
• HANDLE: 2433/120949
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles