人骨格筋の電気生理学的ならびに組織学的研究

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タイトル別名
  • Electrophysiological and Histological Studies on the Human Skeletal Muscle
  • 第1編 人骨格筋の筋線維膜の電気的常数及び膜電位について
  • Part I Electrical Constants of the Membrane of Human Skeletal Muscle Fibers

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The isolated human rectus abdominis muscle and the pectoralis major muscle were used, and these muscles were mounted in constant-temperature bath containing oxygenated Tyrode's solution, and resting potential, action potential and electrical constants of the muscle fiber membrane were measured.<br>1. These muscles are considered to be suitable for the examination of human skeletal muscle fibers in vitro.<br>2. Resting potentials of the rectus abdominis muscle and the pectoralis major muscle are 77.2±7.8 mV and 73.9±9.7 mV repectively, and action potentials of these muscles are 93.9±9.7 mV and 87.2 8.0 mV respectively. These figures are in the same range of any other reported data of the mammalian muscle fiber, but distributions are little wider.<br>3. Durations of action potentials are about 1.9 msec. in both muscles.<br>4. Electrical constants of these muscles are as follows:<br>τm(msec) ρ(μ) Rm (cm) Cm (μF/cm2) λ(mm)<br>M. pectoralis major 7.25±2.14 33±5 1080±325 9.1±4.1 1.39±0.47<br>M. rectus abdominis 8.60±2.22 27±5 1228±187 6.1±2.3 1.15±0.23

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