A novel method for introducing a polyfluoroalkyl group into aromatic compounds

• Tahara, Ryuhei

• Fukuhara, Tadahito

• Hara, Shoji

抄録

Introduction of a polyfluoroalkyl group into aromatic compounds was achieved by Friedel-Crafts reaction using (1-chloro-1-hydroperfluoroalkyl) sulfides 1, and the subsequent desulfurizing-difluorination of the resulting product using IF5/Et3N-nHF. Perfluoroethyl, 1,1,2,2,3,3-hexafluoropropyl, and 1,1,2,2,3,3,4,4,5,5-decafluoropentyl groups were introduced to various aromatic compounds by this method. Selective perfluoroethylation of uracil at the 5-position was also performed.

収録刊行物

• Journal of Fluorine Chemistry

  Journal of Fluorine Chemistry 132 (9), 579-586, 2011-09

  Elsevier B.V.

キーワード

• polyfluoroalkylation
• fluoro-Pummerer rearrangement
• desulfurizing-difluorination
• IF5
• 5-(perfluoroethyl)uracil

詳細情報

• CRID: 1050282813986135808
• NII論文ID: 120003370688
• HANDLE: 2115/47208
• ISSN: 00221139
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles