Surface plasmon resonance in monitoring of complement activation on biomaterials.

• 有馬, 祐介

• Toda, Mitsuaki

• 岩田, 博夫

抄録

When artificial materials come into contact with blood, various biological responses are induced. For successful development of biomaterials used in biomedical devices that will be exposed to blood, understanding and control of these interactions are essential. Surface plasmon resonance (SPR) spectroscopy is one of the surface-sensitive optical methods to monitor biological interactions. SPR enables real-time and in situ analysis of interfacial events associated with biomaterials research. In this review, we describe an SPR biosensor and its application to monitor complement activation onto biomaterials surface. We also discuss the effect of surface properties of the material on complement activation.

収録刊行物

• Advanced drug delivery reviews

  Advanced drug delivery reviews 63 (12), 988-999, 2011-09-16

  Elsevier B.V.

キーワード

• Complement activation
• Surface plasmon resonance
• Self-assembled monolayer
• Polymer coating
• Nonspecific protein adsorption
• The classical pathway
• The alternative pathway

詳細情報

• CRID: 1050564285676893824
• NII論文ID: 120003405538
• NII書誌ID: AA10689127
• ISSN: 0169409X
• HANDLE: 2433/147261
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles