Assessment of bone healing and hypoesthesia in the upper lip after Le Fort I osteotomy with self-setting α-tricalcium phosphate and absorbable plates

• Ueki, Koichiro

• Okabe, Katsuhiko

• Marukawa, Kohei

• Mukozawa, Aya

• Moroi, Akinori

• Miyazaki, Mao

• Sotobori, Megumi

• Ishihara, Yuri

• Yoshizawa, Kunio

• Ooi, Kazuhiro

• Kawashiri, Shuichi

抄録

Purpose: The purpose of this study was to evaluate hypoesthesia of the upper lip and bone formation using self-setting α-tricalcium phosphate (Biopex ®) between the segments following Le Fort I osteotomy with bent absorbable plate fixation. Subjects and methods: The subjects were 47 patients (94 sides) who underwent Le Fort I osteotomy with and without mandibular osteotomy. They were divided into a Biopex ® group (48 sides) and a control group (46 sides). The Biopex ® was inserted into the anterior part of the gap between the segments in the Biopex ® group. Trigeminal nerve hypoesthesia at the region of the upper lip was assessed bilaterally by the trigeminal somatosensory-evoked potential (TSEP) method. The area of the Biopex ® at the anterior part in the maxilla was assessed immediately after surgery and 1 year postoperatively by computed tomography (CT). Results: The mean measurable period and standard deviation were 13.2 ± 18.5 weeks in the control group, 14.5 ± 17.9 weeks in the Biopex ® group, and there was no significant difference in TSEP. The area of the Biopex ® after 1 year was significantly smaller than that immediately after surgery (right side: P = 0.0024, left side: P = 0.0001) and bone defects between the segments could not be found in the Biopex ® group. In the control group, although the areas of bone defect after 1 year were significantly smaller than that immediately after surgery on the right side (P = 0.0133) and left side (P = 0.0469) in the frontal view, complete healing of the bone defects could be seen in 12 of 46 sides after 1 year. Conclusion: This study suggested that inserting Biopex ® in the gap between the maxillary segments was useful for new bone formation and it did not prevent the recovery of upper lip hypoesthesia after Le Fort I osteotomy with absorbable plate fixation. © 2012 European Association for Cranio-Maxillo-Facial Surgery.

収録刊行物

• Journal of Cranio-Maxillofacial Surgery

  Journal of Cranio-Maxillofacial Surgery 41 (2), 129-134, 2013-03-01

  European Association for Cranio-Maxillofacial Surgery / Elsevier

キーワード

• Absorbable plate
• Computed tomography (CT)
• Le Fort I osteotomy
• Self-setting α-tricalcium phosphate (Biopex ®)
• Trigeminal somatosensory-evoked potential (TSEP)

詳細情報

• CRID: 1050564285904340480
• NII論文ID: 120004419381
• NII書誌ID: AA10682955
• ISSN: 10105182
• Web Site: http://hdl.handle.net/2297/31964
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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