Pre- and perioperative factors affecting infection after living donor liver transplantation.

• 海道, 利実

• Mori, Akira

• Ogura, Yasuhiro

• Ogawa, Kouhei

• Hata, Koichiro

• Yoshizawa, Atsushi

• Yagi, Shintaro

• Uemoto, Shinji

抄録

[Objective]: Infectious complications, including sepsis, that often occur after liver transplantation (LT) comprise the most frequent causes of in-hospital death. This study investigated the predictors of post-transplantation infectious complications to establish a strategy with which to improve short-term outcomes after LT. [Methods]: We used univariate and multivariate analyses to assess pre- and perioperative risk factors for post-transplantation infectious complications in 100 consecutive patients who underwent living donor LT from February 2008 through February 2010 at our institute. [Results]: Multivariate analysis showed that low preoperative body cell mass and the absence of preoperative supplementation with branched-chain amino acids were of prognostic significance for post-transplantation sepsis. In addition, Child–Pugh classification C and massive operative blood loss were independent risk factors for post-transplantation bacteremia, and preoperative low body cell mass was an independent risk factor for in-hospital death from infection. [Conclusion]: Pretransplantation nutritional intervention and decreases in operative blood loss would help prevent post-transplantation infectious complications from developing during living donor LT. Branched-chain amino acid supplementation before LT affects the occurrence of infectious complications.

収録刊行物

• Nutrition

  Nutrition 28 (11-12), 1104-1108, 2012-11

  Elsevier Inc.

キーワード

• Liver transplantation
• Infection
• Nutrition
• Body cell mass
• Branched-chain amino acids

詳細情報

• CRID: 1050282810716518528
• NII論文ID: 120004873908
• NII書誌ID: AA11535297
• ISSN: 08999007
• HANDLE: 2433/160282
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles