FDG-PET/CT assessment of misty mesentery: Feasibility for distinguishing viable mesenteric malignancy from stable conditions.

• 中谷, 航也

• Nakamoto, Yuji

• Togashi, Kaori

抄録

[Purpose] "Misty mesentery" is a CT appearance of mesenteric fat changes with increased attenuation often existing with swelled mesenteric lymph nodes. We evaluated diagnostic performance of FDG-PET/CT in distinguishing viable malignant disorders from benign conditions in misty mesentery. [Materials and methods] 4236 FDG-PET/CT images were reviewed to identify patients with appearances of misty mesentery. Only the initial examinations were evaluated. Patients undergoing chemotherapy and/or radiotherapy within 3 months, patients with bulky mesenteric mass, and patients without follow-up examinations were excluded. Maximum short-axis diameter of mesenteric nodules (Diam-max) and maximum standardized uptake value (SUVmax) for mesenteric abnormalities were measured, and the diagnostic performance to differentiate between viable malignancy and stable lesions was assessed by receiver-operating characteristic (ROC) analysis, based on final diagnoses obtained by histology or follow-up examinations. Their significance was assessed by multivariate logistic regression. [Results] 71 studies met the inclusion criteria with confirmed diagnoses (13 viable malignancies; 58 stable lesions). Of the 13 malignant cases, 12 were lymphoma. ROC curves indicated an optimal Diam-max cut-off value of >10 mm and SUVmax cut-off of ≥3.0, with area under the curve of 0.961 and 0.926, respectively. Using the optimal Diam-max cut-off, sensitivity and specificity were 69% and 98%, respectively. Using the optimal SUVmax cut-off, they were 85% and 98%, respectively. The combination of either Diam-max > 10 mm or SUVmax ≥ 3.0 had a sensitivity of 92%. Both Diam-max and SUVmax were significant independent factors for predicting malignancy. [Conclusions] FDG-PET/CT is feasible for identifying viable malignancy in misty mesentery.

収録刊行物

• European journal of radiology

  European journal of radiology 82 (8), e380-e385, 2013-08

  Elsevier Ireland Ltd.

キーワード

• FDG
• PET/CT
• Mesentery
• Mesenteric panniculitis
• Lymphoma

詳細情報

• CRID: 1050001335772545664
• NII論文ID: 120005300468
• ISSN: 0720048X
• DOI: 10.1016/j.ejrad.2013.03.016
• HANDLE: 2433/176336
• Web Site: https://api.elsevier.com/content/article/PII:S0720048X13001629?httpAccept=text/xml
• Web Site: https://api.elsevier.com/content/article/PII:S0720048X13001629?httpAccept=text/plain
• 本文言語コード: en
• 資料種別: journal article
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