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- 辻 博
- 北九州津屋崎病院内科
書誌事項
- タイトル別名
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- Antibodies to Specific Nuclear Antigens in Patients with Yusho
- ユショウ ニ オケル トクイ コウカク コウタイ ノ ケントウ
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抄録
To investigate chronic immune effects of polychlorinated biphenyl (PCB) and polychlorinated dibenzofuran (PCDF), autoantibodies including anti-Smith (Sm) antibody, anti-ribonucleoprotein (RNP) antibody, anti-centromere antibody and anti-double-stranded DNA (dsDNA) antibody, were studied in168 patients with Yusho and 54 controls in2012. Autoatibodies were present in some patients of Yusho ; 1 case (0.6%) for anti-Sm antibody, 4 cases (2.4%) for anti-centromere antibody and 11 cases (6.5%) for anti-dsDNA antibody. However, these autoantibodies were not demonstrated in any controls. There was a significantly higher prevalence of elevated anti-centromere antibody in subjects with high PCB concentration than in those with low PCB concentration. We conclude that anti-centromere antibody is present in patients with Yusho, and it may be associated with blood PCB concentration.
収録刊行物
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- 福岡醫學雜誌
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福岡醫學雜誌 104 (4), 73-77, 2013-04-25
福岡医学会
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詳細情報 詳細情報について
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- CRID
- 1390009224764025600
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- NII論文ID
- 120005303390
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- NII書誌ID
- AN00215478
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- DOI
- 10.15017/26693
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- HANDLE
- 2324/26693
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- NDL書誌ID
- 024893128
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- ISSN
- 0016254X
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- PubMed
- 23858781
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用可