全血中ブチロフェノン系薬物のLC/MS/MSによる迅速分析

• 服部, 秀樹

• 有信, 哲哉

• 岩井, 雅枝

• 水谷, 洋子

• 益田, 健史

• 妹尾, 洋

• 熊澤, 武志

• 李, 暁鵬

• 鈴木, 修

書誌事項

タイトル別名

• RAPID DETERMINATION OF BUTYROPHENONES IN HUMAN WHOLE BLOOD BY LC/MS/MS

抄録

We established a practical and reliable method for rapid and simple analysis for butyrophenones in human hemolyzed blood by LS/MS/MS. Removal of hemoglobin and other large proteins from hemolyzed blood was simply completed using Amicon Ultra-4 centrifugal filter device (MILLIPORE). Six kinds of butyrophenones used in this research were detected with high sensitivity by LC/MS/MS. The detection limit in human hemolyzed blood was about 5 ng/ml except for timiperone and pimozide.

収録刊行物

• 法中毒

  法中毒 22 (2), 132-133, 2004-04-01

  日本法中毒学会

詳細情報

• CRID: 1050001201661874816
• NII論文ID: 120005314062
• ISSN: 09159606
• HANDLE: 10271/1746
• Web Site: https://hama-med.repo.nii.ac.jp/records/1713
• Web Site: https://search.jamas.or.jp/link/ui/2004203078
• 本文言語コード: ja
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles