Rechallenge of Everolimus for Metastatic Renal Cell Carcinoma after Recovery from Grade 3 Interstitial Lung Disease : A Case Report

• Utsunomiya, Noriaki

  The Department of Urology, Kobe City Medical Center General Hospital

• Kono, Yuka

  The Department of Urology, Kobe City Medical Center General Hospital

• Matsumoto, Keiyu

  The Department of Urology, Kobe City Medical Center General Hospital

• Matsumoto, Takeshi

  The Department of Respiratory Medicine, Kobe City Medical Center General Hospital

• Nakagawa, Atsushi

  The Department of Respiratory Medicine, Kobe City Medical Center General Hospital

• Tsunemori, Hiroyuki

  The Department of Urology, Kobe City Medical Center General Hospital

• Okada, Takuya

  The Department of Urology, Kobe City Medical Center General Hospital

• Muguruma, Koei

  The Department of Urology, Kobe City Medical Center General Hospital

• Kawakita, Mutsushi

  The Department of Urology, Kobe City Medical Center General Hospital

Bibliographic Information

Other Title

• Grade3の間質性肺疾患を起こした転移性腎細胞癌に対しエベロリムスの再投与を施行した1例
• Grade 3 ノ カンシツセイ ハイ シッカン オ オコシタ テンイセイジンサイボウガン ニ タイシ エベロリムス ノ サイトウヨ オ シコウ シタ 1レイ

Abstract

We report a case of the rechallenge of everolimus for metastatic renal cell carcinoma (RCC) after successful recovery from grade 3 interstitial lung disease (ILD). A 76-year-old man with metastatic RCC developed grade 3 ILD one month after the initiation of everolimus therapy (10 mg/day). ILD subsided in 4 months after the withdrawal of everolimus and treatment with corticosteroids. Half dose (5 mg/day) of everolimus was rechallenged for 9 months until another grade 3 ILD developed. Everolimus kept the disease under control for 13 months including the discontinuation period.

Journal

• Hinyokika Kiyo

  Hinyokika Kiyo 60 (1), 25-28, 2014-01

  泌尿器科紀要刊行会

Keywords

• RCC
• Everolimus
• Rechallenge
• Interstitial lung disease

Details

• CRID: 1050845760713462144
• NII Article ID: 120005385875
• NII Book ID: AN00208315
• ISSN: 00181994
• HANDLE: 2433/182916
• NDL BIB ID: 025168688
• Web Site: http://id.ndl.go.jp/bib/025168688
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025168688
• Web Site: https://search.jamas.or.jp/link/ui/2014203250
• Text Lang: ja
• Article Type: departmental bulletin paper
• Data Source:
  • IRDB
  • NDL
  • CiNii Articles