Characterization of dipeptidyl peptidase–IV of Porphyromonas gingivalis

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  • Porphyromonas gingivalis のジペプチジル ペプチダーゼ–IV の性状

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Dipeptidyl peptidase IV (DPP–IV) was purified to homogeneity from the crude extract of Porphyromonas gingivalis. Isoelectric point and molecular weight of DPP–IV were 6.1 and 66 kDa, respectively. Km value for the appropriate substrate (H–Gly–Pro–pNA) was 0.2₅ mM, and Vmax/Km was 0.₅2. Optimum pH for the activity was found at pH ₇.₅. DPP–IV was considered a serine enzyme.

収録刊行物

  • 松本歯学

    松本歯学 41 (1), 26-32, 2015-06-30

    松本歯科大学学会

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