Quantitative imaging values of CT, MR, and FDG-PET to differentiate pineal parenchymal tumors and germinomas: are they useful?

• 柿木, 崇秀

• 岡田, 知久

• Kanagaki, Mitsunori

• Yamamoto, Akira

• Fushimi, Yasutaka

• Sakamoto, Ryo

• Arakawa, Yoshiki

• Mikami, Yoshiki

• Shimono, Taro

• Takahashi, Jun C

• Togashi, Kaori

抄録

[Introduction] Quantitative values of CT attenuation, apparent diffusion coefficient (ADC), and standardized uptake value (SUV) were investigated for differentiation between pineal parenchymal tumors (PPTs) and germinomas. Differences in age, sex, and calcification pattern were also evaluated. [Methods] Twenty-three patients with PPTs and germinomas in 20 years were retrospectively enrolled under the approval of the institutional review board. CT attenuation, ADC, and SUV (20, 13, and 10 patients, respectively) were statistically compared between the two tumors. Differences in sex and patterns of calcification (“exploded" or “engulfed") were also examined. Mean patient ages were compared among three groups of pineoblastoma, pineal parenchymal tumor of intermediate differentiation, (PPTID) and pineocytoma and germinoma. [Results]None of the quantitative values of CT attenuation, ADC, and SUV showed significant differences between PPTs and germinomas (p > .05). However, there was a significant difference in age (p < .05) among the three groups of pineoblastoma (mean age ± standard deviation 7.0 ± 8.7 years), PPTID, and pineocytoma (53.7 ± 11.4 years) and germinoma (19.1 ± 8.1 years). Sex also showed significant differences between PPTs and germinomas (p = .039). Exploded pattern of calcification was found in 9 of 11 PPT patients and engulfed pattern in 7 of 9 patients with germinomas. No reverse pattern was observed, and the patterns of calcification were considered highly specific of tumor types.[Conclusions] None of the quantitative imaging values could differentiate PPTs from germinomas. Age, sex, and calcification patterns were confirmed useful in differentiating these tumors to some degree.

収録刊行物

• Neuroradiology

  Neuroradiology 56 (4), 297-303, 2014-02-09

  Springer Berlin Heidelberg

キーワード

• Pineal tumor
• Germinoma
• CT attenuation
• Apparent diffusion coefficient
• Standardized uptake value
• Adolescent
• Adult
• Brain Neoplasms/diagnosis
• Child
• Child, Preschool
• Diagnosis, Differential
• Female
• Fluorodeoxyglucose F18/diagnostic use
• Germinoma/diagnosis
• Humans
• Image Enhancement/methods
• Image Interpretation, Computer-Assisted/methods
• Infant
• Magnetic Resonance Imaging/methods
• Male
• Middle Aged
• Pineal Gland/pathology
• Pineal Gland/radiography
• Pineal Gland/radionuclide imaging
• Pinealoma/diagnosis
• Positron-Emission Tomography/methods
• Radiopharmaceuticals/diagnostic use
• Reproducibility of Results
• Sensitivity and Specificity
• Sex Factors
• Tomography, X-Ray Computed/methods
• Young Adult

詳細情報

• CRID: 1050845760746448896
• NII論文ID: 120005669342
• NII書誌ID: AA00754889
• ISSN: 00283940
• HANDLE: 2433/201495
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles