切除からインプラントを維持源としたエピテーゼまで一貫治療を行った上顎洞悪性線維性組織球腫の1例

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  • A Case of Malignant Fibrous Histiocytoma in the Maxillary sinus : Consistency of Treatment from Tumor Resection to an Orbital Epithesis Supported by Implants
  • セツジョ カラ インプラント オ イジゲン トシタ エピテーゼ マデ イッカン チリョウ オ オコナッタ ジョウガクドウ アクセイ センイセイ ソシキ キュウシュ ノ 1レイ

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A case of malignant fibrous histiocytoma (MFH) arising primarily in the left maxilla is reported. The patient, a 50-year-old man, presented with diffuse swelling of the upper left side of the gingiva. Radiographic findings revealed wide destruction of the left maxilla. Initial biopsy revealed a fibrosarcoma. The patient received continuous arterial infusion of 5-FU and external irradiation with 60Co-40Gy preoperatively. After a combination of chemotherapy and radiotherapy, he received total resection of the left maxilla with orbital exenteration. Histopathologically, the tumor was diagnosed as a storiform-pleomorphic type of MFH. After operation, general chemotherapy with CDDP and external irradiation with 60Co-30Gy were performed. Two years after removal of the tumor, three fixtures were placed into the bony orbital rim to fit an orbital prothesis. There is no clinical evidence of recurrence as of 9.5 years after extirpation of the tumor and the implants are functioning well.

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