ガングリオシドG[M]₃単分子膜中へのカフェ酸エステル類の分布と作用

• 戸泉, 文江

• 月川, 健士

• 横山, 祥子

• といずみ, ふみえ

• TOIZUMI, Fumie

書誌事項

タイトル別名

• ガングリオシド G[M]₃ タンブンシマク チュウ エ ノ カフェサン エステルルイ ノ ブンプ ト サヨウ

抄録

P(論文)

The distribution of benzyl caffeate (BC), phenethyl caffeate (PC) and cinnamyl caffeate (CC) in ganglioside GM3 (GM3) monolayer as a model of a tumor membrane, and the effects of the caffeic acid esters on the GM3 membrane were observed by atomic force microscopy (AFM). BC and PC distributed in the GM3 monolayer formed holes in the GM3 matrix. The effects of BC and PC on the GM3 membrane were similar to those of known antitumor compounds, suggesting that BC and PC may possess antitumor activitiy. The activity of CC seems to be weaker than that of BC and PC. The effects of caffeic acid esters on the GM3 membrane were different from those on the GD3 membranes.

収録刊行物

• 九州保健福祉大学研究紀要 = Journal of Kyushu University of Health and Welfare

  九州保健福祉大学研究紀要 = Journal of Kyushu University of Health and Welfare (18), 63-66, 2017-03-25

  延岡 : 九州保健福祉大学

キーワード

• カフェ酸エステル
• ガングリオシドG[M]₃
• 原子間力顕微法
• 抗腫瘍活性

詳細情報

• CRID: 1050845762568992256
• NII論文ID: 120006328665
• NII書誌ID: AA11490417
• ISSN: 13455451
• NDL書誌ID: 028129384
• Web Site: https://phoenix.repo.nii.ac.jp/records/1304
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I028129384
• Web Site: https://search.jamas.or.jp/link/ui/2017256268
• 本文言語コード: ja
• 資料種別: departmental bulletin paper
• データソース種別:
  • IRDB
  • NDL
  • CiNii Articles