Leisure-time physical activity and risk of disability incidence: A 12-year prospective cohort study among young elderly of the same age at baseline

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  • Matsunaga Takashi
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine
  • Naito Mariko
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine
  • Wakai Kenji
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine
  • Ukawa Shigekazu
    Department of Public Health, Hokkaido University Graduate School of Medicine
  • Zhao Wenjing
    Department of Public Health, Hokkaido University Graduate School of Medicine
  • Okabayashi Satoe
    Kyoto University Health Service
  • Ando Masahiko
    Center for Advanced Medicine and Clinical Research, Nagoya University Hospital
  • Kawamura Takashi
    Kyoto University Health Service
  • Tamakoshi Akiko
    Department of Public Health, Hokkaido University Graduate School of Medicine

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<p>Background: To clarify the role of physical activity in preventing disability in Japan, we investigated the association between amount of leisure-time physical activity and incidence of disability among the young elderly.</p><p>Methods: In the New Integrated Suburban Seniority Investigation (NISSIN) project conducted from 1996 to 2013, we followed 2888 community-dwelling adults aged 64–65 years with no history of cerebrovascular disease for a median follow-up of 11.6 years. Disabilities were defined as follows based on the classifications of the Japanese long-term care insurance system: 1) support or care levels (support levels 1–2 or care levels 1–5); 2) care levels 2–5; 3) support or care levels with dementia; and 4) care levels 2–5 or death. In addition, we also assessed 5) all-cause mortality.</p><p>Results: After controlling for sociodemographic, lifestyle, and medical factors, male participants reporting an activity level of 18.1 metabolic equivalent (MET)-hours/week (the median among those with activities) or more had 52% less risk of being classified as support or care levels with dementia compared with the no activity group (hazard ratio 0.48; 95% confidence interval, 0.25–0.94). No significant association was found among women between amount of leisure-time physical activity and incidence of disability.</p><p>Conclusion: We identified an inverse dose–response relationship between the amount of leisure-time physical activity and the risk of disability with dementia in men. Therefore, a higher level of physical activity should be recommended to young elderly men to prevent disability with dementia.</p>

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