この論文をさがす
抄録
A 22-year-old Japanese male with trisomy 21 was diagnosed with West syndrome at 4 months old. After the suppression of epileptic spasms using adrenocorticotropic hormone therapy, he had complex partial seizures and bilateral frontal epileptic discharges on EEG. Although the introduction of topiramate (TPM) decreased the seizures during wakefulness, frequent episodes of brief eye-opening appeared during sleep while the patient was taking TPM (400 mg/day). EEG showed fast activity at the times of eye-opening. The episodes of eye-opening during sleep and the fast activities disappeared upon TPM discontinuation. This is the first report of TPM-induced microseizures similar to benzodiazepine-induced microseizures.
収録刊行物
-
- Acta Medica Okayama
-
Acta Medica Okayama 72 (4), 419-422, 2018-08
Okayama University Medical School
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390290699797862656
-
- NII論文ID
- 120006501289
-
- NII書誌ID
- AA00508441
-
- ISSN
- 0386300X
-
- PubMed
- 30140091
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- IRDB
- PubMed
- CiNii Articles