Nano-honeycomb electrode based QCM sensor and its application for PPI detection

• Asai, Naoto

• Matsumoto, Naohiro

• Kazama, Nozomi

• Nagaoka, Yasuo

• Sumiyoshi, Takaaki

• Shimizu, Tomohiro

• 新宮原, 正三

• Ito, Takeshi

抄録

An anodic aluminon oxide (AAO)-based nano honeycomb electrode was coated on a quartz crystal for use as a sensing device in a quartz crystal microbalance (QCM) to monitor the protein-protein interactions (PPIs). As examples, we detected PPIs of anti-Bcl-2 and Bcl-2, and Bcl-2 and Bax in real time. A sensor with a flat Au electrode showed a tiny frequency shift upon sample injection. However, our fabricated device could detect 10 μg/mL of Bcl-2 and Bax in sequence.

2016年度関西大学研究拠点形成支援経費

収録刊行物

• IEEE Sensors Journal

  IEEE Sensors Journal 2019-02-11

  IEEE

キーワード

• Biosensor
• quartz crystal microbalance (QCM)
• protein-protein interaction
• real time detecting
• 関西大学
• Kansai University
• 関西大学研究拠点形成支援経費

詳細情報

• CRID: 1050001202915836160
• NII論文ID: 120006583276
• ISSN: 1530437X
• HANDLE: 10112/16606
• Web Site: https://kansai-u.repo.nii.ac.jp/records/680
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles