Endoscopic resection is a suitable initial treatment strategy for oxyntic gland adenoma or gastric adenocarcinoma of the fundic gland type

• Iwamuro, Masaya

• Kusumoto, Chiaki

• Nakagawa, Masahiro

• Kobayashi, Sayo

• Yoshioka, Masao

• Inaba, Tomoki

• Toyokawa, Tatsuya

• Hori, Shinichiro

• Tanaka, Shouichi

• Matsueda, Kazuhiro

• Tanaka, Takehiro

• Okada, Hiroyuki

抄録

The aim of this study was to reveal the histological features of oxyntic gland adenomas and gastric adenocarcinoma of the fundic-gland type (GA-FG). We retrospectively examined the histological features of 126 lesions of oxyntic gland adenoma and/or GA-FG in 116 patients. The prevalence of oxyntic gland adenomas and GA-FG was approximately equal. The majority of the lesions were resected by endoscopic mucosal resection using a diathermic snare (EMR, n=42) or endoscopic submucosal dissection (ESD, n=72). Histologically, there were no lesions with invasion at the level of the muscularis propria or deeper, and lymphovascular invasion was present in 1.6%. Of the ESD and EMR specimens, there were no lesions that were positive for vertical margins. Among the eight GA-FG patients with deep (>= 500 mu m) submucosal invasion, six were treated with endoscopic resection alone, and no recurrence was documented. No patients died of the disease during the median follow-up period of 14.5 months. In conclusion, all lesions were confined to the mucosa or submucosa and were negative for vertical margins. Lymphovascular invasion was present in only 1.6% of the patients. Thus, we believe that endoscopic resection is a suitable initial treatment method for oxyntic gland adenoma and GA-FG.

収録刊行物

• Scientific Reports

  Scientific Reports 11 (1), 2021-04-01

  Nature Research

詳細情報

• CRID: 1050006432243823744
• NII論文ID: 120007029876
• ISSN: 20452322
• Web Site: https://ousar.lib.okayama-u.ac.jp/61911
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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  • CiNii Articles