Localization of the Candidate Genes ELOVL5 and SCD1 for Male Effect' Pheromone Synthesis in Goats (Capra hircus)
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- KITAGO Masaru
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MOMOZAWA Yukihide
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MASUDA Koji
- Laboratory of Veterinary Ethology, The University of Tokyo
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- WAKABAYASHI Yoshihiro
- Laboratory of Veterinary Ethology, The University of Tokyo
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- DATE-ITO Atsuko
- Laboratory of Veterinary Ethology, The University of Tokyo Single Molecule Project, Tokyo Metropolitan Institute of Medical Science
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- HAGINO-YAMAGISHI Kimiko
- Single Molecule Project, Tokyo Metropolitan Institute of Medical Science
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- KIKUSUI Takefumi
- Laboratory of Veterinary Ethology, The University of Tokyo
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- TAKEUCHI Yukari
- Laboratory of Veterinary Ethology, The University of Tokyo
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- MORI Yuji
- Laboratory of Veterinary Ethology, The University of Tokyo
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抄録
The `male effect' is a well-known phenomenon in female sheep and goats, whereby pheromone-induced activation of reproductive function occurs. In a previous study, we showed that the genes for elongation of long-chain fatty acids family member 5 (ELOVL5) and stearoyl-CoA desaturase 1 (SCD1) increased their expression significantly, concomitant with induction of pheromone synthesis. Therefore, these genes were considered to be prime candidate genes for pheromone synthesis. In the present study, we performed in situ hybridization to investigate where these two genes are expressed in goat skin. Strong positive signals were detected for both genes in the head skin of the male goat, which is the main site of pheromone production, and were mainly in the basal layer of the sebaceous gland cells, with the remaining cells showing negligible signals. None of the cells in the rump skin of the male goat or the head skin of the orchidectomized goat, neither of which produce pheromone, exhibited strong positive signals. The present study demonstrates that expression of these two candidate genes for pheromone synthesis is primarily localized in the sebaceous glands of the pheromone-producing skin region.<br>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 53 (6), 1329-1333, 2007
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390282681312754432
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- NII論文ID
- 130000054439
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- NII書誌ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 9327264
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
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