Effects of Phytosterol Esters on Serum Lipids and Fecal Steroids Excretion in Hamsters
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- KOJIMA Keiichi
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- SEKI Shinji
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- HIDAKA Ichiro
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- YOSHINO Hisako
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- NOGUCHI Osamu
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- SATO Chiemi
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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- AOYAMA Toshiaki
- Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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We investigated the effects of phytosterol esters on serum lipids and fecal steroids excretion. Golden Syrian Hamsters were fed diets containing 100 g of control oil, free phytosterol (FPS) oil or phytosterol ester (PSE) oil per kilogram of feed supplemented with cholesterol (2 g/kg feed), for 15 or 29 days. Each oil contained 0.36%, 3.71%, or 3.69% FPS or FPS-equivalent PSE, respectively. The serum total cholesterol concentrations in hamsters fed the FPS diet (216 ± 6 mg/dL) or the PSE diet (220 ± 5 mg/dL) were significantly lower compared with those fed the control diet (239 ± 6 mg/dL) at day 29 (p<0.05). There was no significant difference in the ratio of non-HDL-cholesterol to HDL-cholesterol in any group at the same determination point. Fecal cholesterol excretion increased in hamsters fed the FPS diet and the PSE diet compared with those fed the control diet. These results suggest that PSE effectively lowers blood cholesterol, and that there is no difference between FPS and PSE regarding their cholesterol lowering effect.<br>
収録刊行物
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- Journal of Oleo Science
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Journal of Oleo Science 52 (5), 229-237, 2003
公益社団法人 日本油化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204093260672
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- NII論文ID
- 130000060420
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- NII書誌ID
- AA11503337
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- COI
- 1:CAS:528:DC%2BD3sXjtlyhtLg%3D
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- ISSN
- 13473352
- 13458957
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- NDL書誌ID
- 6507508
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 使用不可