Antioxidative, Antihyaluronidase and Antityrosinase Activities of Some Constituents from the Aerial Part of Piper elongatum VAHL.

• MASUOKA Chikako

  School of Agriculture, Kyushu Tokai University

• ONO Masateru

  School of Agriculture, Kyushu Tokai University

• ITO Yasuyuki

  School of Agriculture, Kyushu Tokai University

• NOHARA Toshihiro

  Faculty of Pharmaceutical Sciences, Kumamoto University

抄録

Seven known compounds, pyrroside B (1), swertisin (2), isovitexin (3), isoswertiajaponin (4), vomifoliol (blumenol A) (5), (6S,9R)-roseoside (6) and angelicoidenol (7) were isolated from the methanol (MeOH) extract of the aerial part of Piper elongatum VAHL. and their structures were identified on the basis of physical and spectral data. In addition, the antioxidative activity of 1–4 was evaluated by the ferric thiocyanate method. All these compounds showed stronger antioxidative activity than that of α-tocopherol. Furthermore, the scavenging effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH), the antihyaluronidase and the antityrosinase activities of 1–4, asebogenin (8), 2′,6′-dihydroxy-4′-methoxydihydrochalcone (9), 3-geranyl-4-methoxybenzoic acid (10), 3-geranyl-4-hydroxybenzoic acid (11), nervogenic acid (12) and 2,2-dimethyl-6-carboxyl-8-prenyl-chromene (13), which were previously isolated from the MeOH extract were evaluated. Compounds 4, 8 and 9 showed higher radical scavenging effect than that of L-cysteine, and 4, 8 and 11 exhibited stronger inhibition effect on the activation of hyaluronidase than that of tranilast. Compound 8 indicated almost the same antityrosinase activity as that of kojic acid.<br>

収録刊行物

• Food Science and Technology Research

  Food Science and Technology Research 9 (2), 197-201, 2003

  公益社団法人 日本食品科学工学会

キーワード

• <i>Piper elongatum</i> VAHL.
• flavonoid glycoside
• antioxidative effect
• radical scavenger
• antihyaluronidase activity
• antityrosinase activity

詳細情報

• CRID: 1390001204454142336
• NII論文ID: 130000061377
• NII書誌ID: AA11320122
• DOI: 10.3136/fstr.9.197
• COI: 1:CAS:528:DC%2BD3sXmvFSgsrw%3D
• ISSN: 18813984
• ISSN: 13446606
• ISSN: http://id.crossref.org/issn/13446606
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可