Pregnancy and Parturition of Mice Latently Infected with Pseudorabies Virus

• TANAKA Seiichi

  Division of Laboratory Animal Sciences, Department of Life Science, Institute of Scientific Research, Oita University

• MANNEN Kazuaki

  Division of Laboratory Animal Sciences, Department of Life Science, Institute of Scientific Research, Oita University

抄録

In this study, the influence of pregnancy and parturition on mice in a mouse model of latent infection with Pseudorabies virus (PrV) was analyzed. Latently infected (LI) female mice were paired with mature uninfected males. The mating produced progeny without any clinical signs of Aujeszky's Disease. At weaning, both male and female progeny of LI mice showed significantly lower weight than control mice. PrV was not detected from nasal swab specimens of the female parent mice or the trigeminal ganglia of all mice, except 3 of 50 neonatal mice. These findings demonstrate that pregnancy and parturition induce little reactivation of latent PrV, but do affect the mother's body, as indicated by the decreased weight of progeny at weaning.<br>

収録刊行物

• Experimental Animals

  Experimental Animals 57 (2), 149-152, 2008

  公益社団法人 日本実験動物学会

キーワード

• latency
• pregnancy
• Pseudorabies virus

詳細情報

• CRID: 1390001205047516800
• NII論文ID: 130000067994
• NII論文ID: 10024166326
• NII書誌ID: AA11032321
• DOI: 10.1538/expanim.57.149
• ISSN: 18817122
• ISSN: 00075124
• ISSN: 13411357
• NDL書誌ID: 9455660
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9455660
• Web Site: http://www.jstage.jst.go.jp/article/expanim/57/2/57_2_149/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008232151
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可