Hypoglycemic Syncope Induced by a Combination of Cibenzoline and Angiotensin Converting Enzyme Inhibitor.
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- Ogimoto Akiyoshi
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Hamada Mareomi
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Saeki Hideyuki
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Hiasa Go
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Ohtsuka Tomoaki
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Hashida Hidetoshi
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Hara Yuji
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Okura Takafumi
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Shigematsu Yuji
- the Second Department of Internal Medicine, Ehime University School of Medicine
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- Hiwada Kunio
- the Second Department of Internal Medicine, Ehime University School of Medicine
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抄録
A 65-year-old Japanese woman with dilated cardiomyopathy, hypothyroidism and refractory sustained ventricular tachycardia experienced a near-death hypoglycemic syncope. The attack seemed to be induced by a high level of serum insulin, probably due to cibenzoline and by concomitant use of an angiotensin converting enzyme inhibitor (ACEI). Additionally, decreased food intake because of a severe toothache may have contributed to the deterioration of her condition. This case warns cardiologists that a combined cibenzoline and ACEI therapy can provoke serious adverse effects such as hypoglycemic syncope in the elderly. Therefore, the possibility of a hypoglycemic attack associated with these drugs should be explained to patients who are in poor condition. <br>
収録刊行物
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- Japanese Heart Journal
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Japanese Heart Journal 42 (2), 255-259, 2001
International Heart Journal刊行会