Thyrotoxic Periodic Paralysis Induced by Pulse Methylprednisolone

DOI Web Site 参考文献8件
  • Wongraoprasert Somporn
    Division of Endocrine and Metabolism, Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University
  • Buranasupkajorn Patinut
    Division of Endocrine and Metabolism, Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University
  • Sridama Vitaya
    Division of Endocrine and Metabolism, Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University
  • Snabboon Thiti
    Division of Endocrine and Metabolism, Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University

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We present a young Thai man who developed acute flaccid paralysis after receiving pulse methylprednisolone for chronic inflammatory demyelinating polyneuropathy. Hypokalemia from intracellular shift was confirmed by calculation of transtubular potassium gradient (TTKG). His muscle strength and serum potassium fully recovered with a small amount of potassium replacement. Graves' disease was subsequently diagnosed and treated with radioactive iodine. We suggest that acute paralysis after the use of steroids should raise a suspicion of thyrotoxic periodic paralysis (TPP). The potential mechanisms of steroid-induced TPP are discussed.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 46 (17), 1431-1434, 2007

    一般社団法人 日本内科学会

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