MRI Findings from a Case of Fulminating Adult-onset Measles Encephalitis
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- Jin Kazutaka
- Department of Neurology, Iwate National Hospital
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- Sato Shigeru
- Department of Neurology, Kohnan Hospital
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- Saito Ryuji
- Department of Neurology, Kohnan Hospital
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- Ohnuma Ayumu
- Department of Neurology, Kohnan Hospital
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- Nomura Hiroshi
- Department of Neurology, Kohnan Hospital
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- Itoyama Yasuto
- Department of Neurology, Tohoku University School of Medicine
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We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatous state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 45 (12), 783-787, 2006
一般社団法人 日本内科学会