Angioimmunoblastic T-Cell Lymphoma Initially Presenting with Replacement of Bone Marrow and Peripheral Plasmacytosis

• Sakai Hisashi

  Department of Internal Medicine, Takeda General Hospital

• Tanaka Hideaki

  Department of Internal Medicine, Takeda General Hospital

• Katsurada Tatsuya

  Department of Hematology, Takeda General Hospital

• Yoshida Yataro

  Department of Hematology, Takeda General Hospital

• Okamoto Eiichi

  Department of Pathology, Takeda General Hospital

• Ohno Hitoshi

  Department of Internal Medicine, Takeda General Hospital

抄録

A 73-year-old man presented with lymphadenopathy, hepatosplenomegaly, and a variety of hematological and immunological abnormalities. The bone marrow was replaced by polymorphic cellular infiltrates containing aggregates of CD10⁺ T-cells. Circulating lymphoplasmacytic/immunoblastic cells showed an early plasma cell immunophenotype on flow cytometric analysis. Combination of these observations indicated that the underlying disorder of this patient was angioimmunoblastic T-cell lymphoma (AITL); postmortem pathology was consistent with progression of peripheral T-cell lymphoma. Even in the absence of definitive lymph node biopsy, the appearance of the bone marrow and the peripheral blood can lead to the diagnosis of AITL.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 46 (7), 419-424, 2007

  一般社団法人 日本内科学会

キーワード

• angioimmunoblastic T-cell lymphoma
• bone marrow replacement
• immunohistochemistry
• CD10⁺ T-cell
• plasma cell

詳細情報

• CRID: 1390001204871623040
• NII論文ID: 130000078774
• DOI: 10.2169/internalmedicine.46.6121
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/46/7/46_7_419/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007256216
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可