Peripheral T-cell Lymphoma Following Diffuse Large B-cell Lymphoma Associated with Celiac Disease

DOI Web Site 参考文献22件
  • Makishima Hideki
    Department of Internal Medicine, Division of Hematology, Shinshu University School of Medicine
  • Komiyama Yuichi
    Department of Internal Medicine, Aizawa Hospital
  • Asano Naoko
    Department of Pathology and Clinical Laboratories, Nagoya University School of Medicine
  • Momose Kayoko
    Department of Internal Medicine, Division of Hematology, Shinshu University School of Medicine
  • Nakamura Shigeo
    Department of Pathology and Clinical Laboratories, Nagoya University School of Medicine
  • Ishida Fumihiro
    Department of Internal Medicine, Division of Hematology, Shinshu University School of Medicine

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抄録

Celiac disease is a risk factor for lymphoma. Previously, we reported a case of diffuse large B-cell lymphoma (DLBCL) associated with celiac disease in a Japanese patient. Without any signs of DLBCL recurrence, he suddenly developed gastrointestinal symptoms and subcutaneous masses after resuming a gluten-containing diet. Peripheral T-cell lymphoma (PTCL) was diagnosed. Although a complete response was seen for 8 months, he was later admitted again with pleural and pericardial effusion due to PTCL. Expression of cytotoxic molecules, CCR4 and CXCR4 were all confirmed in PTCL cells, and the patient died soon afterwards. Clinically speaking, even though no gastrointestinal symptoms were seen, a gluten-free diet should have been strongly recommended for this patient.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 47 (4), 295-298, 2008

    一般社団法人 日本内科学会

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