Gianotti-Crosti Syndrome Caused by Acute Hepatitis B Virus Genotype D Infection

  • MICHITAKA Kojiro
    Endoscopy Center, Ehime University School of Medicine
  • HORIIKE Norio
    Third Department of Internal Medicine, Ehime University School of Medicine
  • CHEN Yan
    Third Department of Internal Medicine, Ehime University School of Medicine
  • DUONG Tran Nhu
    Third Department of Internal Medicine, Ehime University School of Medicine
  • KONISHI Ichiro
    Third Department of Internal Medicine, Ehime University School of Medicine
  • MASHIBA Toshie
    Third Department of Internal Medicine, Ehime University School of Medicine
  • TOKUMOTO Yoshio
    Third Department of Internal Medicine, Ehime University School of Medicine
  • HIASA Yoichi
    Third Department of Internal Medicine, Ehime University School of Medicine
  • TANAKA Yasuhito
    Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences
  • MIZOKAMI Masashi
    Department of Internal Medicine and Molecular Science, Nagoya City University Graduate School of Medical Sciences
  • ONJI Morikazu
    Third Department of Internal Medicine, Ehime University School of Medicine

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抄録

A 12-year-old girl with Gianotti-Crosti syndrome caused by hepatitis B virus (HBV) infection was admitted due to eruption on her extremities. Laboratory findings revealed elevation of transaminase, positivity for HB surface antigen (HBsAg), and an IgM type anti-HB core. The eruption and level of transaminase improved, and HBsAg became negative within 2 months of onset. Analysis of the virus revealed it to be genotype D with a genomic length of 3, 182 bases and the HBsAg serotype was ayw3, which is very rare in Japan. The possible relationship between Gianotti-Crosti syndrome and HBV genotype D infection is discussed.

収録刊行物

  • Internal Medicine

    Internal Medicine 43 (8), 696-699, 2004

    一般社団法人 日本内科学会

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