Leukemoid Reaction in Association with Bone Marrow Necrosis due to Metastatic Prostate Cancer

DOI Web Site Web Site 参考文献21件
  • AZUMA Taichi
    First Department of Internal Medicine, Ehime University School of Medicine
  • SAKAI Ikuya
    First Department of Internal Medicine, Ehime University School of Medicine
  • MATSUMOTO Takuya
    First Department of Internal Medicine, Ehime University School of Medicine
  • OZAWA Akira
    Department of Urology, Ehime University School of Medicine
  • TANJI Nozomu
    Department of Urology, Ehime University School of Medicine
  • WATANABE Akito
    Ehime Prefectural Imabari Hospital
  • UCHIDA Naoyuki
    First Department of Internal Medicine, Ehime University School of Medicine
  • NARUMI Hirosi
    First Department of Internal Medicine, Ehime University School of Medicine
  • YAKUSHIJIN Yoshihiro
    First Department of Internal Medicine, Ehime University School of Medicine
  • HATO Takaaki
    Division of Blood Transfusion, Ehime University School of Medicine
  • YASUKAWA Masaki
    First Department of Internal Medicine, Ehime University School of Medicine
  • FUJITA Shigeru
    First Department of Internal Medicine, Ehime University School of Medicine

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抄録

An 80-year-old man presented to the internist with fever, fatigue and leukocytosis up to 66.8×103/μl. Although a chronic myelogenous leukemia was initially suspected, he was diagnosed as metastatic bone marrow tumor with bone marrow necrosis from primary prostate cancer on the basis of the clinical and pathological findings. The serum concentrations of IL-6 and TNF-α were mildly elevated to 65.0 pg/ml and, 54.0 pg/ml respectively. It is probable that these humoral factors were partially responsible for the leukemoid reaction although other factors induced by the bone marrow necrosis with bone marrow metastasis of prostate cancer are also likely involved.

収録刊行物

  • Internal Medicine

    Internal Medicine 44 (10), 1093-1096, 2005

    一般社団法人 日本内科学会

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