Facilitation of reflex swallowing from the pharynx and larynx

• Kitagawa Junichi

  Department of Physiology, Nihon University School of Dentistry Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry

• Nakagawa Kazuharu

  Department of Dysphagia Rehabilitation, Nihon University School of Dentistry

• Hasegawa Momoko

  Department of Orthodontics, Nihon University School of Dentistry

• Iwakami Tomoyo

  Department of Dysphagia Rehabilitation, Nihon University School of Dentistry

• Shingai Tomio

  Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences

• Yamada Yoshiaki

  Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences

• Iwata Koichi

  Department of Physiology, Nihon University School of Dentistry Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry Division of Applied System Neuroscience, Advanced Medical Research Center, Nihon University Graduate School of Medical Science

抄録

To evaluate the cooperative effect of afferent signals from the pharynx and larynx on reflex swallowing, the interactive effect of afferent signals from the pharyngeal branch of the glossopharyngeal nerve (GPN-ph) and superior laryngeal nerve (SLN) was analyzed in detail in urethane-anesthetized rats. The electromyographic activity of the mylohyoid muscle was recorded as an indicator of swallowing activity. The onset latency of reflex swallowing was measured to evaluate the effects of electrical stimulation of these nerves, and found to become shorter following an increase in the GPN-ph and/or SLN stimulus frequency. During simultaneous electrical stimulation of the GPN-ph and SLN (frequency: 5-10 Hz, intensity: 30 μA, duration: 1.0 ms for each), the onset latency of reflex swallowing became shorter than that for stimulation of each nerve independently. The present findings suggest that spatiotemporal summation of afferent signals from the GPN-ph and SLN results in an increase of motoneuronal activity in the medullary swallowing center, thus enhancing reflex swallowing. (J Oral Sci 51, 167-171, 2009)

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ｏｒａｌ　Ｓｃｉｅｎｃｅ

  Ｊｏｕｒｎａｌ　ｏｆ　Ｏｒａｌ　Ｓｃｉｅｎｃｅ 51 (2), 167-171, 2009

  日本大学歯学部

キーワード

• glossopharyngeal nerve
• superior laryngeal nerve
• pharyngeal reflex
• deglutition
• swallowing

詳細情報

• CRID: 1390001205047048320
• NII論文ID: 130000126106
• DOI: 10.2334/josnusd.51.167
• ISSN: 18804926
• ISSN: 13434934
• Web Site: https://www.jstage.jst.go.jp/article/josnusd/51/2/51_2_167/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2010012129
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可