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- ISOLA Michela
- Department of Cytomorphology, University of Cagliari
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- COSSU Margherita
- Department of Cytomorphology, University of Cagliari
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- DE LISA Antonello
- Urologic Clinic, University of Cagliari
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- ISOLA Raffaella
- Department of Cytomorphology, University of Cagliari
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- MASSA Denise
- Department of Cytomorphology, University of Cagliari
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- CASTI Alberto
- Department of Cytomorphology, University of Cagliari
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- SOLINAS Paola
- Department of Cytomorphology, University of Cagliari
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- LANTINI M. Serenella
- Department of Cytomorphology, University of Cagliari
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抄録
Oxytocin is a cyclic nonapeptide whose best known effects are stimulation of uterine smooth muscle cells during labor and of milk ejection during lactation. Circulating oxytocin originates from the hypothalamus, but its production has also been documented in peripheral tissues. Furthermore, seminal plasma also contains oxytocin, but its functional role is still unknown, although its secretion is generally ascribed to the prostate. In this study, we investigated the possibility that seminal oxytocin is also secreted by other exocrine glands of the human male genital tract. Intramural (Littrè's) glands isolated from bioptic specimens of normal urethrae were processed for immunogold localization of oxytocin. Immunostaining was detected in principal cells, with gold particles specifically found on secretory granules. Basal and endocrine cells were unstained. The present findings suggest that urethral glands not only produce the mucinous layer that protects and lubricates the urethral wall, but also are potential sources of other seminal components, such as oxytocin, which probably play still unclear roles in reproductive physiology.<br>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 56 (1), 94-97, 2010
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390282681312943744
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- NII論文ID
- 10026323663
- 130000130545
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- NII書誌ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 10581730
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可