Hypolipidemic Effect of Arborium Plus in Experimentally Induced Hypercholestermic Rabbits
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- MURTY Devarakonda
- Shri Vishnu College of Pharmacy, Vishnupur, Bhimavaram
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- RAJESH Enjamoori
- All India Institute of Medical Sciences
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- RAGHAVA Doonaboina
- Shri Vishnu College of Pharmacy, Vishnupur, Bhimavaram
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- RAGHAVAN Tangaraj Vijaya
- Department of Pharmacology Faculty of Engineering and Technology, Annamalai University
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- SURULIVEL Mukanthan Karupiah Munirajan
- Department of Pharmacology Faculty of Engineering and Technology, Annamalai University
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Abstract
Hypercholesteremia is one of the risk factors for coronary artery disease. The present study highlights the efficacy of the ayurvedic herbal formulation Arborium Plus [Hyppophae ramnoides L. fruit juice (S) and Rhododendron arboreum Sm. Linn flower juice (R) in a 1:4 ratio] on triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), atherogenic index (AI), high-density lipoprotein (HDL), and high-sensitivity c-reactive protein (hs CRP) in experimentally induced hypercholesterolemic rabbits. Four groups of rabbits were subjected to different treatments for 8 weeks: control group, CHOL group (1% w/w cholesterol for 8 weeks), S+R group (1% w/w cholesterol and Arborium Plus for 8 weeks), and A group (1% w/w cholesterol and atorvastatin for 8 weeks). The results showed significant increases in TG, TC, LDL, AI, and hs CRP in hypercholesterolemic rabbits which was significantly reduced in Arborium Plus-treated hypercholesterolemic rabbits. The data demonstrated that the Arborium Plus formulation was associated with hypolipidemic effects in experimentally induced hypercholesterolemic rabbits.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 130 (6), 841-846, 2010-06-01
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001206127118336
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- NII Article ID
- 130000259476
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- NII Book ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 10725857
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed