Pathology: Aggressive spindle cell rhabdomyosarcoma in an 11-month-old boxer dog
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- ROZA Marcello Rodrigues da
- School of Veterinary Medicine, Federal University of Goiás
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- AMORIM Rivadávio Fernandes Batista de
- Department of Pathology, School of Medicine, University of Brasília (UnB)
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- CARNEIRO Fabiana Pirani
- Department of Pathology, School of Medicine, University of Brasília (UnB)
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- BENATTO Nara
- Sante Laboratory
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- BARRIVIERA Mauricio
- Department of Radiology, School of Dentistry, Catholic University of Brasilia
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- MIGUEL Márcia Cristina da Costa
- Post-Graduate Program in Oral Pathology, School of Dentistry, Federal University of Rio Grande do Norte (UFRN)
書誌事項
- タイトル別名
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- Aggressive Spindle Cell Rhabdomyosarcoma in an 11-Month-Old Boxer Dog
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Rhabdomyosarcoma (RMS) is a malignant neoplasm derived from mesenchymal tissue with a tendency toward myogenic differentiation associated with the embryogenesis of skeletal muscle. According to the histological features, it can be classified in embryonal, botryoid, alveolar, and pleomorphic, which usually correspond to clinical behavior and prognosis. The spindle cell (SCRMS) variant is a rare subtype of the embryonal RMS and is considered to be less aggressive lesion. The aim of the present paper is to report an unusual case of SCRMS in an 11-month-old male boxer dog diagnosed as extensive SCRMS that affected the frontal region of the skull. Due to the aggressive nature of the lesion and poor clinical prognosis the dog's owners preferred euthanasia as a treatment. A full postmortem examination was carried out. Microscopically, the lesion was composed of a highly cellular proliferation of spindle cells arranged in long and intersecting fascicles. After performing the immunohistochemical studies (HHF-35, smooth muscle actin, desmin and MyoD1), the present case was diagnosed as SCRMS.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 72 (10), 1363-1366, 2010
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206428697216
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- NII論文ID
- 130000264213
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 10878986
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可