Isolation of Candida Species is an Important Clue for Suspecting Gastrointestinal Tract Perforation as a Cause of Empyema

• Ishiguro Takashi

  Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center

• Takayanagi Noboru

  Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center

• Ikeya Tomohiko

  Department of Thoracic Surgery, Saitama Cardiovascular and Respiratory Center

• Yoshioka Hiroaki

  Department of Laboratory Medicine, Saitama Cardiovascular and Respiratory Center

• Yanagisawa Tsutomu

  Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center

• Hoshi Eishin

  Department of Thoracic Surgery, Saitama Cardiovascular and Respiratory Center

• Hoshi Toshiko

  Department of Radiology, Saitama Cardiovascular and Respiratory Center

• Sugita Yutaka

  Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center

• Kawabata Yoshinori

  Department of Pathology, Saitama Cardiovascular and Respiratory Center

抄録

Background Empyema due to Candida species is a rare entity, and the significance of isolation of Candida species from the pleural effusion is not fully understood. <br> Objective To elucidate the clinical features of Candida empyema. <br> Methods We retrospectively reviewed the cases of 128 patients with culture-positive empyema. <br> Results These 128 patients included 7 whose cause of empyema was esophago- or gastropleural fistula. Empyema was due to Candida species in 5 of the 7 patients. Primary diseases of these 5 patients were spontaneous esophageal rupture in 3 patients, esophageal rupture due to lung cancer invasion in 1 patient, and gastric ulcer perforation in 1 patient. None of these 5 patients had esophageal candidiasis. Among the 121 other patients with empyema not due to esophago- or gastropleural fistula, no patient had empyema due to Candida. <br> Conclusion We believe that the empyema in these 5 patients was caused by normal commensal Candida species entering the pleural cavity when the fistula between the gastrointestinal tract and pleural cavity was formed. Isolation of Candida species can be an important clue for suspecting gastrointestinal tract perforation as a cause of empyema.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 49 (18), 1957-1964, 2010

  一般社団法人 日本内科学会

キーワード

• empyema
• <i>Candida</i> species
• esophageal rupture
• stomach perforation

詳細情報

• CRID: 1390282679847160576
• NII論文ID: 130000336883
• DOI: 10.2169/internalmedicine.49.3667
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/49/18/49_18_1957/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011120984
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可