Cardiac Angiosarcoma Diagnosed by Transvenous Endomyocardial Biopsy With the Aid of Transesophageal Echocardiography and Intra-Procedural Consultation
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- Hosokawa Yusuke
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Kodani Eitaro
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Kusama Yoshiki
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Kamiya Masataka
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Yoshikawa Masatomo
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Hirasawa Yasuhiro
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Nakagomi Akihiro
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Atarashi Hirotsugu
- Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital
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- Maeda Shotaro
- Department of Pathology, Nippon Medical School Tama-Nagayama Hospital
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- Mizuno Kyoichi
- Department of Internal Medicine (Division of Cardiology, Hepatology, Geriatric, and Integrated Medicine), Nippon Medical School
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We report a case who had confirmed tumor cells in the biopsy specimens by transvenous endomyocardial biopsy with intra-procedural consultation and fast smear cytology. A 57-year-old female was admitted to our hospital because of shortness of breath and left back pain. Transthoracic echocardiography (TTE) and contrast-enhanced computed tomography (CT) scans demonstrated a large mass in the right atrium and multiple liver tumors thought to be due to spread of the disease. Coronary angiography showed the right coronary artery was involved in the mass. In order to confirm the histological diagnosis, we attempted transvenous endomyocardial tumor biopsy under fluoroscopic guidance. However, we failed to obtain adequate tissue material. Due to several risks associated with a surgical procedure such as an open surgical biopsy, transvenous endomyocardial tumor biopsy was again attempted with the aid of transesophageal echocardiography (TEE). Intra-procedural consultation and fast smear cytology enabled us to finish the procedure. Hematoxylin-eosin stained sections demonstrated spindle-shaped cells. Immunohistochemical stains of these cells were positive for anti-factor VIII antigen, CD31, and CD34. These findings indicated a definite diagnosis of angiosarcoma. Since there was no surgical indication for this tumor, the patient underwent chemotherapy with docetaxel and radiotherapy. Three months later, CT scans showed a reduction in the size of the cardiac tumor.
収録刊行物
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- International Heart Journal
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International Heart Journal 51 (5), 367-369, 2010
一般社団法人 インターナショナル・ハート・ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390001205225632128
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- NII論文ID
- 130000410617
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- ISSN
- 13493299
- 13492365
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
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