A Case of Membranous Nephropathy with Primary Biliary Cirrhosis and Cyclosporine-induced Remission

DOI Web Site 被引用文献1件 参考文献19件
  • Sakamaki Yusuke
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan
  • Hayashi Matsuhiko
    Center for Apheresis and Dialysis, Keio University, Japan
  • Wakino Shu
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan
  • Fukuda Seiichi
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan
  • Konishi Kounosuke
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan
  • Hashiguchi Akinori
    Department of Pathology, Keio University, Japan
  • Hayashi Koichi
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan
  • Itoh Hiroshi
    Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, Japan

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抄録

We report a case of membranous nephropathy with primary biliary cirrhosis (PBC). A 76-year-old Japanese man had been treated for PBC and was referred to our department because of acute severe proteinuria (10 g/day). Renal biopsy was performed and was compatible with a diagnosis of membranous nephropathy. The patient was treated with cyclosporine A (CsA; Neoral®), which was followed by normalization of liver function and partial remission of proteinuria (0.68 g/day) within six months without any significant side effects. This case suggests that CsA monotherapy is effective for the treatment of both liver dysfunction and membranous nephropathy associated with PBC.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50 (3), 233-238, 2011

    一般社団法人 日本内科学会

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