24-Hour Recording of Parkinsonian Gait Using a Portable Gait Rhythmogram

• Mitoma Hiroshi

  Department of Medical Education, Tokyo Medical University

• Yoneyama Mitsuru

  Mitsubishi Chemical Group Science and Technology Research Center, Inc.

• Orimo Satoshi

  Department of Neurology, Kanto Chuo Hospital

抄録

Objective In the advanced stage of Parkinson's disease (PD), motor fluctuation is a frequent and a disabling problem. Despite its importance, motor fluctuation has received little scientific analysis probably due to limitation in objective assessment. Here, we focused on gait disorders to estimate motor fluctuation in daily activities.<br> Patients and Methods Using a new device, the portable gait rhythmogram, we recorded gait rhythm continuously over 24 hours in 22 patients with PD and in 11 normal controls, for quantitative evaluation of motor fluctuation. The duration of one gait cycle was measured.<br> Results Continuous 24-hour recording identified changes in gait rhythm, which correlated with fluctuation of PD symptoms. Different motor fluctuations were observed; a shift to a faster gait cycle was noted in patients with short-step walking, festination or freezing of gait, whereas a shift to a slower gait cycle was observed in patients with bradykinesia or instability.<br> Conclusion Characterization of motor fluctuation using this device could help in the selection of appropriate anti-PD medications.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 49 (22), 2401-2408, 2010

  一般社団法人 日本内科学会

キーワード

• Parkinson's disease
• gait disorder
• motor fluctuation

詳細情報

• CRID: 1390001204872694528
• NII論文ID: 130000413367
• DOI: 10.2169/internalmedicine.49.3511
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/49/22/49_22_2401/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011177161
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
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