Long-term Effect of an Enteral Diet with a Different n-6/n-3 Ratio on Fatty Acid Composition and Blood Parameters in Rats

DOI Web Site Web Site 参考文献12件
  • Watanabe Nakamichi
    Department of Food Science and Nutrition, Faculty of Human Ecology, Showa Women’s University
  • Onuma Kozue
    Department of Food Science and Nutrition, Faculty of Human Ecology, Showa Women’s University
  • Fujimoto Kenshiro
    Department of Food and Nutrition, Koriyama Women’s University
  • Miyake Shizuko
    R & D Laboratories, EN Otsuka Pharmaceutical Co., Ltd.
  • Nakamura Tsuyoshi
    Department of Nutrition and Health Science, Fukuoka Women’s University

この論文をさがす

抄録

The n-6/n-3 ratio of polyunsaturated fatty acids (PUFAs) in enteral feeding formulas is not considered to be important, because the short-term administration of these formulas has been the norm for postoperative digestive organs. However, the long-term administration of enteral feeding formulas has been increasingly recommended for patients with aging-associated aphagia. This study is aimed at investigating the effect of the long-term administration of an enteral feeding formula containing n-3 polyunsaturated fatty acids (PUFAs) on the fatty acid composition of endogenous phospholipids. Rats, which were initially fed a diet lacking n-3 PUFAs for 2 generations, were subsequently fed an enteral feeding formula containing or lacking n-3 PUFAs for 12 weeks (n = 10). Then, the fatty acid composition of phospholipids in the brain, liver, red blood cells, and plasma of the rats was analyzed. Although the fatty acid composition of neural tissues is suggested to be not affected by diet, the n-6/n-3 ratio of phospholipids in the brains of rats that were fed an enteral feeding formula containing n-3 PUFAs was significantly lower than those of rats that were fed a formula lacking n-3 PUFAs. The enteral feeding formula containing n-3 PUFAs may be effective for the regulation of brain functions and the prevention of atherosclerosis.

収録刊行物

参考文献 (12)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ