Molecular and Phenotypic Characteristics of CMY-2 .BETA.-Lactamase-Producing Salmonella enterica Serovar Typhimurium Isolated from Cattle in Japan

• SUGAWARA Masaru

  Aizu Livestock Hygiene Service Center

• KOMORI Junko

  Iwaki Livestock Hygiene Service Center

• KAWAKAMI Marimo

  Kenchu Livestock Hygiene Service Center

• IZUMIYA Hidemasa

  Department of Bacteriology, National Institute of Infectious Diseases

• WATANABE Haruo

  Department of Bacteriology, National Institute of Infectious Diseases

• AKIBA Masato

  Safety Research Team, National Institute of Animal Health

抄録

Isolates of extended-spectrum cephalosporin (ESC)-resistant Salmonella enterica serovar Typhimurium obtained from two different farms in Fukushima Prefecture, Japan, in 2007 were characterized in order to determine the genetic basis of resistance. ESC resistance in the two isolates was mediated by an AmpC β-lactamase encoded by the bla_CMY-2 gene, which is located in a large self-transmissible plasmid in each isolate. The sizes of the bla_CMY-2-carrying plasmids were different. The replicon types of the plasmids were I1-Iγ and A/C. The results of macrorestriction analysis and phage typing suggest a close relationship between both isolates. This is the first report of ESC-resistant S. Typhimurium isolated from cattle in Japan.<br>

収録刊行物

• Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ

  Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ 73 (3), 345-349, 2011

  公益社団法人 日本獣医学会

キーワード

• AmpC β-lactamase
• <i>bla</i>_CMY-2
• ESC-resistant <i>Salmonella</i>
• <i>Salmonella</i> Typhimurium

詳細情報

• CRID: 1390282681404811008
• NII論文ID: 130000444194
• DOI: 10.1292/jvms.10-0156
• ISSN: 13477439
• ISSN: 09167250
• Web Site: http://www.jstage.jst.go.jp/article/jvms/73/3/73_10-0156/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可