Fulminant Myelopathy following Neurogenic Proximal Weakness Associated with Human T-Cell Lymphotropic Virus Type I Infection

  • Yamashita Satoshi
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
  • Ueda Akihiko
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
  • Hirahara Tomoo
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
  • Kimura En
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
  • Hirano Teruyuki
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan
  • Uchino Makoto
    Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan

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抄録

We report a patient with human T-cell lymphotropic virus type I (HTLV-I) infection, who presented with proximal extremity neurogenic muscular weakness followed by fulminant myelopathy, but with no upper motor symptoms. The symptoms were inconsistent with the World Health Organization or El Escorial criteria for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or amyotrophic lateral sclerosis (ALS). This case indicates that fulminant myelopathy without upper motor neuronal symptoms may occur long after the onset of HTLV-I-associated neurogenic proximal muscular weakness. Additionally, we report that treatment with high-dose steroid pulse therapy partially improves symptoms of lightning pain and sensory disturbance.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50 (8), 919-924, 2011

    一般社団法人 日本内科学会

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