Steady and Temporary Expressions of Smooth Muscle Actin in Hair, Vibrissa, Arrector Pili Muscle, and Other Hair Appendages of Developing Rats

• Morioka Kiyokazu

  Laboratory of Electron Microscopy, The Tokyo Metropolitan Institute of Medical Science Department of Bioengineering, School of Bioscience and Biotechnology, Tokyo Institute of Technology

• Arai Mary

  Division of Resources Life Science, The United Graduate School of Agricultural Sciences, Tottori University

• Ihara Setsunosuke

  Division of Resources Life Science, The United Graduate School of Agricultural Sciences, Tottori University Department of Biological Science, Faculty of Life and Environmental Science, Shimane University

抄録

The hair erection muscle, arrector pili, is a kind of smooth muscle located in the mammalian dermis. The immunohistochemical study using an antibody against smooth muscle alpha actin (SMA) showed that the arrector pili muscle develops approximately 1–2 weeks after birth in dorsal and ventral skin, but thereafter they degenerate. The arrector pili muscle was not detected in the mystacial pad during any stage of development, even in the neighboring pelage-type hair follicle. A strong signal of SMA in the skin was located in the dermal sheath as well as in some outer root sheath cells in the hair and vibrissal follicles. Positive areas in the dermal and outer root sheaths were restricted to a lower moiety, particularly areas of similar height, where keratinization of the hair shaft occurs. This rule is valid for both pelage hair follicles and vibrissal follicles. At medium heights of the follicle, SMA staining in the dermal sheath was patchy and distant from the boundary between dermis and epidermis. In contrast to SMA, vimentin was expressed over the entire height of the dermal sheath. Unlike the arrector pili muscle, the expression of SMA in the dermal sheath was observed during fetal, neonatal, and adult stages. The presence of actin-myosin and vimentin fibers in supporting cells is thought to be beneficial for the hair follicle to cope with the movement of the hair shaft, which may be caused by physical contacts with outside materials or by the contraction of internal muscles.<br>

収録刊行物

• Ａｃｔａ　Ｈｉｓｔｏｃｈｅｍｉｃａ　ｅｔ　Ｃｙｔｏｃｈｅｍｉｃａ

  Ａｃｔａ　Ｈｉｓｔｏｃｈｅｍｉｃａ　ｅｔ　Ｃｙｔｏｃｈｅｍｉｃａ 44 (3), 141-153, 2011

  日本組織細胞化学会

キーワード

• hair
• arrector pili muscle
• smooth muscle actin
• vimentin
• dermal sheath

詳細情報

• CRID: 1390001204863446272
• NII論文ID: 130000722778
• DOI: 10.1267/ahc.11013
• ISSN: 13475800
• ISSN: 00445991
• Web Site: http://www.jstage.jst.go.jp/article/ahc/44/3/44_11013/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012169561
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可