高タンパク質飼料の摂取がめん羊のカルシウム代謝に及ぼす影響

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タイトル別名
  • Effect of a High Protein Diet on Calcium Metabolism in Sheep
  • コウ タンパクシツ シリョウ ノ セッシュ ガ メンヨウ ノ カルシウム タイ

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The effects of a high protein diet on calcium (Ca) handling in the kidney and Ca mobilization were evaluated in sheep. Utilizing a cross-over design, a clearance study and a EDTA infusion study were conducted in six adult wethers fed a control diet (CP: 9.9%, ME: 2.02 Mcal/kg) or a high protein diet (CP: 19.6%, ME: 2.02Mcal/kg). Urinary Ca excretion was increased and plasma Ca concentrations were decreased by the high protein diet. An increase in glomerular filtration rate would be responsible for an increase in filtered Ca across glomeruli and an increase in urinary Ca excretion. The high protein diet also elevated plasma free hydroxyproline level. Although plasma ionized Ca concentrations linearly decreased in both dietary treatments during intravenous EDTA infusion, the rate of reduction in ionized Ca concentrations tended to be smaller in sheep fed the high protein diet than in sheep fed the control diet. Before EDTA infusion, plasma immunoreactive parathyroid hormone (iPTH) level was increased in sheep fed the high protein diet. However, the increase in iPTH level was smaller in sheep fed the high protein diet than that in those fed the control diet. Ca mobilization from available Ca pool was stimulated by the high protein diet. This study indicates that a high protein diet increases urinary Ca excretion and depresses plasma Ca levels, leading to activate bone Ca resorption in sheep.

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  • 日本畜産学会報

    日本畜産学会報 62 (7), 628-635, 1991

    公益社団法人 日本畜産学会

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